Defects behave very differently than perfect crystalline material and often control key properties. Our research group works at the interface of materials science, engineering, and physics to understand how defects can be understood and engineered. We discover new structure-property relationships in nanostructured materials and advanced alloys for next-generation structural, electronic, and energy components, as well as increase the reliability and lifetime of these materials. To achieve these goals, we use a combination of cutting-edge experimental, characterization, and computational techniques.